Liver Cancer Cell Lines
Database

LCCL to predict drug response

Molecular Features

Search Gene:

Mutations and CNAs (15119)
Gene nameAlteration typeVariant classAnnotation transcriptgNomencNomenpNomenPPH pr├ędictionCell Line
CTNNB1MutationIn-FrameENST00000349496.5
g.41265568_41266630del
g.41265568_41266630del
c.9_427del
c.9_427del
p.Ala5_Gln143del
p.Ala5_Gln143del
damaging
damaging
HepG2
EME2MutationIn-FrameENST00000568449.1
g.1825822_1825824delCTC
g.1825822_1825824delCTC
c.806_808del
c.806_808del
p.Ser269del
p.Ser269del
damaging
damaging
HepG2
SLC26A11MutationIn-FrameENST00000361193.3
g.78196560_78196562del
g.78196560_78196562del
c.341_343del
c.341_343del
p.Phe114del
p.Phe114del
damaging
damaging
HepG2
BPIMutationIn-FrameENST00000262865.4
g.36936015_36936016insCAA
g.36936015_36936016insCAA
c.189_190insCAA
c.189_190insCAA
p.Ile63_Lys64insGln
p.Ile63_Lys64insGln
damaging
damaging
HepG2
GTF3C5MutationIn-FrameENST00000372097.5
g.135933304_135933306del
g.135933304_135933306del
c.1497_1499del
c.1497_1499del
p.Glu499del
p.Glu499del
damaging
damaging
HepG2
TRIM64CMutationIn-FrameENST00000530230.1
g.49080591_49080592insGGGTCTATG
g.49080591_49080592insGGGTCTATG
c.74_75insATAGACCCC
c.74_75insATAGACCCC
p.Val26X
p.Val26X
damaging
damaging
Hep3B
RCE1MutationIn-FrameENST00000309657.3
g.66610978_66610986del
g.66610978_66610986del
c.52_60del
c.52_60del
p.Glu18_Pro20del
p.Glu18_Pro20del
damaging
damaging
Hep3B
DUOX2MutationIn-FrameENST00000389039.6
g.45394038_45394058del
g.45394038_45394058del
c.2784_2804del
c.2784_2804del
p.Asp930_Arg936del
p.Asp930_Arg936del
damaging
damaging
Hep3B
TSHZ2MutationIn-FrameENST00000371497.5
g.51870084_51870086del
g.51870084_51870086del
c.87_89del
c.87_89del
p.Glu34del
p.Glu34del
damaging
damaging
Hep3B
IL17RCMutationIn-FrameENST00000295981.3
g.9959222_9959223insTCTGGTCTT
g.9959222_9959223insTCTGGTCTT
c.223_224insTCTGGTCTT
c.223_224insTCTGGTCTT
p.Leu74_Ser75insPheTrpSer
p.Leu74_Ser75insPheTrpSer
damaging
damaging
Hep3B
MPDZMutationIn-FrameENST00000319217.7
g.13196173_13196175del
g.13196173_13196175del
c.1601_1603del
c.1601_1603del
p.Glu534del
p.Glu534del
damaging
damaging
Hep3B
NUDT17MutationIn-FrameENST00000334513.5
g.145586670_145586675del
g.145586670_145586675del
c.901_906del
c.901_906del
p.Lys301_Ser302del
p.Lys301_Ser302del
damaging
damaging
HepaRG
HIST1H3AMutationIn-FrameENST00000357647.3
g.26020735_26020740del
g.26020735_26020740del
c.18_23del
c.18_23del
p.Gln6_Ala8delinsHis
p.Gln6_Ala8delinsHis
damaging
damaging
HepaRG
CDKN1AMutationIn-FrameENST00000244741.5
g.36652015_36652029del
g.36652015_36652029del
c.137_151del
c.137_151del
p.Arg46_Phe51delinsLeu
p.Arg46_Phe51delinsLeu
damaging
damaging
HepaRG
RAB44MutationIn-FrameNM_001257357.1
g.36689831_36689832insGGTGCA
g.36689831_36689832insGGTGCA
c.1921_1922insGTGCAG
c.1921_1922insGTGCAG
p.Ala640_Val641insGlyAla
p.Ala640_Val641insGlyAla
damaging
damaging
B1
ASCC1MutationIn-FrameENST00000342444.4
g.73862691_73862692ins33
g.73862691_73862692ins33
c.1075_1076insGCAAAAAAAAGGAAAAAAAAACATAGTATCTAT
c.1075_1076insGCAAAAAAAAGGAAAAAAAAACATAGTATCTAT
p.Asp359_Ser400delins8X
p.Asp359_Ser400delins8X
damaging
damaging
HCC.3
RERGLMutationIn-FrameENST00000229002.2
g.18234192_18234193ins153
g.18234192_18234193ins153
c.550_551insTGACATGGAGACATAGAATGTTACTGCTAGACCAGACACTCCAAATGAAAGAAGTGCTGCCATAACTGCAGCCCCAGAATTTGGCAATCTCTGGTATCTCAGTCAGGTCAATGATAGGATGACAACAGAGGAAAGAGAACAATTCCCCACAGG
c.550_551insTGACATGGAGACATAGAATGTTACTGCTAGACCAGACACTCCAAATGAAAGAAGTGCTGCCATAACTGCAGCCCCAGAATTTGGCAATCTCTGGTATCTCAGTCAGGTCAATGATAGGATGACAACAGAGGAAAGAGAACAATTCCCCACAGG
p.Pro184_Val205delins21X
p.Pro184_Val205delins21X
damaging
damaging
HCC.3
CYFIP1MutationIn-FrameENST00000313077.7
g.22954235_22954240del
g.22954235_22954240del
c.1385_1390del
c.1385_1390del
p.Gln462_Val463del
p.Gln462_Val463del
damaging
damaging
HCC.3
GZF1MutationIn-FrameENST00000338121.5
g.23345961_23345963del
g.23345961_23345963del
c.941_943del
c.941_943del
p.Lys314del
p.Lys314del
damaging
damaging
HCC.3
SFI1MutationIn-FrameENST00000400288.2
g.32014362_32014363insCTG
g.32014362_32014363insCTG
c.3687_3688insCTG
c.3687_3688insCTG
p.Ala1229_Cys1230insLeu
p.Ala1229_Cys1230insLeu
damaging
damaging
HCC.3
ALDOBMutationIn-FrameENST00000374855.4
g.104192168_104192170del
g.104192168_104192170del
c.191_193del
c.191_193del
p.Phe64del
p.Phe64del
damaging
damaging
HCC.3
TSC1MutationIn-FrameENST00000298552.3
g.135771988_135771989insGCT
g.135771988_135771989insGCT
c.3128_3129insAGC
c.3128_3129insAGC
p.Ser1043delinsArgAla
p.Ser1043delinsArgAla
damaging
damaging
HCC.3
ARHGAP29MutationIn-FrameENST00000260526.6
g.94640194_94640199del
g.94640194_94640199del
c.3012_3017del
c.3012_3017del
p.Asn1004_Val1006delinsLys
p.Asn1004_Val1006delinsLys
damaging
damaging
HCC.1.1
C10orf90MutationIn-FrameENST00000284694.7
g.128192896_128192897insCGA
g.128192896_128192897insCGA
c.872_873insTCG
c.872_873insTCG
p.Ser291_Leu292insArg
p.Ser291_Leu292insArg
damaging
damaging
HCC.1.1
TRIM44MutationIn-FrameENST00000299413.5
g.35684956_35684973del
g.35684956_35684973del
c.297_314del
c.297_314del
p.Ser107_Glu112del
p.Ser107_Glu112del
damaging
damaging
HCC.1.1
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