Liver Cancer Cell Lines
Database

LCCL to predict drug response

Mutations and CNAs (15119)

Gene nameFilter by Gene name	Alteration type	Variant class	Annotation transcript	gNomen	cNomen	pNomen	PPH prédiction	Cell LineFilter by Cell Line
CTNNB1	Mutation	In-Frame	ENST00000349496.5	g.41265568_41266630del g.41265568_41266630del	c.9_427del c.9_427del	p.Ala5_Gln143del p.Ala5_Gln143del	damaging damaging	HepG2
EME2	Mutation	In-Frame	ENST00000568449.1	g.1825822_1825824delCTC g.1825822_1825824delCTC	c.806_808del c.806_808del	p.Ser269del p.Ser269del	damaging damaging	HepG2
SLC26A11	Mutation	In-Frame	ENST00000361193.3	g.78196560_78196562del g.78196560_78196562del	c.341_343del c.341_343del	p.Phe114del p.Phe114del	damaging damaging	HepG2
BPI	Mutation	In-Frame	ENST00000262865.4	g.36936015_36936016insCAA g.36936015_36936016insCAA	c.189_190insCAA c.189_190insCAA	p.Ile63_Lys64insGln p.Ile63_Lys64insGln	damaging damaging	HepG2
GTF3C5	Mutation	In-Frame	ENST00000372097.5	g.135933304_135933306del g.135933304_135933306del	c.1497_1499del c.1497_1499del	p.Glu499del p.Glu499del	damaging damaging	HepG2
TRIM64C	Mutation	In-Frame	ENST00000530230.1	g.49080591_49080592insGGGTCTATG g.49080591_49080592insGGGTCTATG	c.74_75insATAGACCCC c.74_75insATAGACCCC	p.Val26X p.Val26X	damaging damaging	Hep3B
RCE1	Mutation	In-Frame	ENST00000309657.3	g.66610978_66610986del g.66610978_66610986del	c.52_60del c.52_60del	p.Glu18_Pro20del p.Glu18_Pro20del	damaging damaging	Hep3B
DUOX2	Mutation	In-Frame	ENST00000389039.6	g.45394038_45394058del g.45394038_45394058del	c.2784_2804del c.2784_2804del	p.Asp930_Arg936del p.Asp930_Arg936del	damaging damaging	Hep3B
TSHZ2	Mutation	In-Frame	ENST00000371497.5	g.51870084_51870086del g.51870084_51870086del	c.87_89del c.87_89del	p.Glu34del p.Glu34del	damaging damaging	Hep3B
IL17RC	Mutation	In-Frame	ENST00000295981.3	g.9959222_9959223insTCTGGTCTT g.9959222_9959223insTCTGGTCTT	c.223_224insTCTGGTCTT c.223_224insTCTGGTCTT	p.Leu74_Ser75insPheTrpSer p.Leu74_Ser75insPheTrpSer	damaging damaging	Hep3B
MPDZ	Mutation	In-Frame	ENST00000319217.7	g.13196173_13196175del g.13196173_13196175del	c.1601_1603del c.1601_1603del	p.Glu534del p.Glu534del	damaging damaging	Hep3B
NUDT17	Mutation	In-Frame	ENST00000334513.5	g.145586670_145586675del g.145586670_145586675del	c.901_906del c.901_906del	p.Lys301_Ser302del p.Lys301_Ser302del	damaging damaging	HepaRG
HIST1H3A	Mutation	In-Frame	ENST00000357647.3	g.26020735_26020740del g.26020735_26020740del	c.18_23del c.18_23del	p.Gln6_Ala8delinsHis p.Gln6_Ala8delinsHis	damaging damaging	HepaRG
CDKN1A	Mutation	In-Frame	ENST00000244741.5	g.36652015_36652029del g.36652015_36652029del	c.137_151del c.137_151del	p.Arg46_Phe51delinsLeu p.Arg46_Phe51delinsLeu	damaging damaging	HepaRG
RAB44	Mutation	In-Frame	NM_001257357.1	g.36689831_36689832insGGTGCA g.36689831_36689832insGGTGCA	c.1921_1922insGTGCAG c.1921_1922insGTGCAG	p.Ala640_Val641insGlyAla p.Ala640_Val641insGlyAla	damaging damaging	B1
ASCC1	Mutation	In-Frame	ENST00000342444.4	g.73862691_73862692ins33 g.73862691_73862692ins33	c.1075_1076insGCAAAAAAAAGGAAAAAAAAACATAGTATCTAT c.1075_1076insGCAAAAAAAAGGAAAAAAAAACATAGTATCTAT	p.Asp359_Ser400delins8X p.Asp359_Ser400delins8X	damaging damaging	HCC.3
RERGL	Mutation	In-Frame	ENST00000229002.2	g.18234192_18234193ins153 g.18234192_18234193ins153	c.550_551insTGACATGGAGACATAGAATGTTACTGCTAGACCAGACACTCCAAATGAAAGAAGTGCTGCCATAACTGCAGCCCCAGAATTTGGCAATCTCTGGTATCTCAGTCAGGTCAATGATAGGATGACAACAGAGGAAAGAGAACAATTCCCCACAGG c.550_551insTGACATGGAGACATAGAATGTTACTGCTAGACCAGACACTCCAAATGAAAGAAGTGCTGCCATAACTGCAGCCCCAGAATTTGGCAATCTCTGGTATCTCAGTCAGGTCAATGATAGGATGACAACAGAGGAAAGAGAACAATTCCCCACAGG	p.Pro184_Val205delins21X p.Pro184_Val205delins21X	damaging damaging	HCC.3
CYFIP1	Mutation	In-Frame	ENST00000313077.7	g.22954235_22954240del g.22954235_22954240del	c.1385_1390del c.1385_1390del	p.Gln462_Val463del p.Gln462_Val463del	damaging damaging	HCC.3
GZF1	Mutation	In-Frame	ENST00000338121.5	g.23345961_23345963del g.23345961_23345963del	c.941_943del c.941_943del	p.Lys314del p.Lys314del	damaging damaging	HCC.3
SFI1	Mutation	In-Frame	ENST00000400288.2	g.32014362_32014363insCTG g.32014362_32014363insCTG	c.3687_3688insCTG c.3687_3688insCTG	p.Ala1229_Cys1230insLeu p.Ala1229_Cys1230insLeu	damaging damaging	HCC.3
ALDOB	Mutation	In-Frame	ENST00000374855.4	g.104192168_104192170del g.104192168_104192170del	c.191_193del c.191_193del	p.Phe64del p.Phe64del	damaging damaging	HCC.3
TSC1	Mutation	In-Frame	ENST00000298552.3	g.135771988_135771989insGCT g.135771988_135771989insGCT	c.3128_3129insAGC c.3128_3129insAGC	p.Ser1043delinsArgAla p.Ser1043delinsArgAla	damaging damaging	HCC.3
ARHGAP29	Mutation	In-Frame	ENST00000260526.6	g.94640194_94640199del g.94640194_94640199del	c.3012_3017del c.3012_3017del	p.Asn1004_Val1006delinsLys p.Asn1004_Val1006delinsLys	damaging damaging	HCC.1.1
C10orf90	Mutation	In-Frame	ENST00000284694.7	g.128192896_128192897insCGA g.128192896_128192897insCGA	c.872_873insTCG c.872_873insTCG	p.Ser291_Leu292insArg p.Ser291_Leu292insArg	damaging damaging	HCC.1.1
TRIM44	Mutation	In-Frame	ENST00000299413.5	g.35684956_35684973del g.35684956_35684973del	c.297_314del c.297_314del	p.Ser107_Glu112del p.Ser107_Glu112del	damaging damaging	HCC.1.1

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Liver Cancer Cell Lines Database

Molecular Features

Liver Cancer Cell Lines
Database