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iver
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ancer
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ell
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ines
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LCCL to predict drug response
Drug: Refametinib
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Refametinib
BAY 86-9766
MEK1/2
MAPK/ERK signaling
Phase 1, 2
Phase 2
Selleck Chemicals
S1089
Cell Line (34)
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AUC
GI50
HepG2
0.57
10.0
JHH1
0.67
0.45
HepaRG
0.74
1.8
HCC.1.2
0.78
2.15
JHH5
0.78
1.8
Hep3B
0.82
3.8
SNU387
0.83
10.0
SNU886
0.88
10.0
SNU182
0.89
10.0
Huh7
0.9
0.125
SNU398
0.91
10.0
JHH7
0.92
10.0
Huh6
0.92
10.0
SNU878
0.93
2.9
JHH2
0.94
10.0
Record: 1 - 15 of 34, pages: 1/3
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Rows Per Page
15
30
60
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LCCL transcriptomic subgroup:
CL1
CL2
CL3
undef.
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