Liver Cancer Cell Lines
Database

LCCL to predict drug response

Molecular Features

Search Gene:

Mutations and CNAs (24)
Gene nameAlteration typeVariant classAnnotation transcriptgNomencNomenpNomenPPH pr├ędictionCell Line
OBSCNMutationMissenseENST00000284548.11
g.228548329C>T
g.228548329C>T
c.19736C>T
c.19736C>T
p.Ala6579Val
p.Ala6579Val
benign
benign
Hep3B
OBSCNMutationMissenseENST00000284548.11
g.228432266A>T
g.228432266A>T
c.3475A>T
c.3475A>T
p.Ile1159Phe
p.Ile1159Phe
possibly damaging
possibly damaging
HCC.1.2
OBSCNMutationMissenseENST00000570156.2
g.228461096A>T
g.228461096A>T
c.6110A>T
c.6110A>T
p.D2037V
p.D2037V
NA
NA
HCC.3
OBSCNMutationMissenseENST00000284548.11
g.228505746G>A
g.228505746G>A
c.14003G>A
c.14003G>A
p.Arg4668Gln
p.Arg4668Gln
possibly damaging
possibly damaging
SNU182
OBSCNMutationMissenseENST00000570156.2
g.228447336C>A
g.228447336C>A
c.4996C>A
c.4996C>A
p.L1666M
p.L1666M
NA
NA
SNU398
OBSCNMutationMissenseENST00000284548.11
g.228402024G>T
g.228402024G>T
c.1408G>T
c.1408G>T
p.Ala470Ser
p.Ala470Ser
benign
benign
SNU449
OBSCNMutationMissenseENST00000284548.11
g.228505423C>T
g.228505423C>T
c.13820C>T
c.13820C>T
p.Pro4607Leu
p.Pro4607Leu
probably damaging
probably damaging
SNU475
OBSCNMutationMissenseENST00000284548.11
g.228494090C>T
g.228494090C>T
c.11677C>T
c.11677C>T
p.Arg3893Trp
p.Arg3893Trp
probably damaging
probably damaging
Huh7
OBSCNMutationMissenseENST00000284548.11
g.228400443C>T
g.228400443C>T
c.959C>T
c.959C>T
p.Thr320Ile
p.Thr320Ile
probably damaging
probably damaging
PLC.PRF5
OBSCNMutationMissenseENST00000284548.11
g.228468357T>C
g.228468357T>C
c.8057T>C
c.8057T>C
p.Leu2686Pro
p.Leu2686Pro
probably damaging
probably damaging
PLC.PRF5
OBSCNMutationMissenseENST00000284548.11
g.228528465C>A
g.228528465C>A
c.17573C>A
c.17573C>A
p.Ala5858Glu
p.Ala5858Glu
probably damaging
probably damaging
PLC.PRF5
OBSCNMutationMissenseENST00000284548.11
g.228468098C>T
g.228468098C>T
c.7882C>T
c.7882C>T
p.Arg2628Cys
p.Arg2628Cys
benign
benign
HLE
OBSCNMutationMissenseENST00000284548.11
g.228468098C>T
g.228468098C>T
c.7882C>T
c.7882C>T
p.Arg2628Cys
p.Arg2628Cys
benign
benign
HLF
OBSCNMutationMissenseENST00000570156.2
g.228459896G>A
g.228459896G>A
c.5960G>A
c.5960G>A
p.R1987Q
p.R1987Q
NA
NA
Huh6
OBSCNMutationMissenseENST00000284548.11
g.228481122C>T
g.228481122C>T
c.10936C>T
c.10936C>T
p.Arg3646Trp
p.Arg3646Trp
benign
benign
Huh6
OBSCNMutationMissenseENST00000284548.11
g.228456234C>T
g.228456234C>T
c.4865C>T
c.4865C>T
p.Pro1622Leu
p.Pro1622Leu
benign
benign
JHH2
OBSCNMutationMissenseENST00000284548.11
g.228469708G>A
g.228469708G>A
c.8272G>A
c.8272G>A
p.Val2758Ile
p.Val2758Ile
possibly damaging
possibly damaging
JHH2
OBSCNMutationMissenseENST00000284548.11
g.228469825C>T
g.228469825C>T
c.8389C>T
c.8389C>T
p.Arg2797Trp
p.Arg2797Trp
probably damaging
probably damaging
JHH2
OBSCNMutationMissenseENST00000284548.11
g.228471240T>G
g.228471240T>G
c.8774T>G
c.8774T>G
p.Leu2925Arg
p.Leu2925Arg
probably damaging
probably damaging
JHH2
OBSCNMutationMissenseENST00000284548.11
g.228471318G>A
g.228471318G>A
c.8852G>A
c.8852G>A
p.Gly2951Asp
p.Gly2951Asp
benign
benign
JHH4
OBSCNMutationMissenseENST00000284548.11
g.228461605G>C
g.228461605G>C
c.5272G>C
c.5272G>C
p.Glu1758Gln
p.Glu1758Gln
possibly damaging
possibly damaging
JHH5
OBSCNMutationMissenseENST00000284548.11
g.228463548C>A
g.228463548C>A
c.6041C>A
c.6041C>A
p.Pro2014Gln
p.Pro2014Gln
probably damaging
probably damaging
SNU368
OBSCNMutationMissenseENST00000422127.1
g.228560647T>C
g.228560647T>C
c.22168T>C
c.22168T>C
p.Ser7390Pro
p.Ser7390Pro
benign
benign
SNU368
OBSCNMutationTruncatingENST00000284548.11
g.228520646del
g.228520646del
c.15731+7del
c.15731+7del
p.?
p.?
damaging
damaging
HepG2
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