Liver Cancer Cell Lines
Database

LCCL to predict drug response

Molecular Features

Search Gene:

Mutations and CNAs (31)
Gene nameAlteration typeVariant classAnnotation transcriptgNomencNomenpNomenPPH prédictionCell Line
TP53MutationIn-FrameENST00000269305.4
g.7578269_7578280del
g.7578269_7578280del
c.569_580del
c.569_580del
p.Pro190_His193del
p.Pro190_His193del
damaging
damaging
JHH5
TP53MutationMissenseENST00000269305.4
g.7578475G>A
g.7578475G>A
c.455C>T
c.455C>T
p.Pro152Leu
p.Pro152Leu
probably damaging
probably damaging
B1
TP53MutationMissenseENST00000269305.4
g.7577548C>T
g.7577548C>T
c.733G>A
c.733G>A
p.Gly245Ser
p.Gly245Ser
probably damaging
probably damaging
HCC.1.2
TP53MutationMissenseENST00000269305.4
g.7578205C>A
g.7578205C>A
c.644G>T
c.644G>T
p.Ser215Ile
p.Ser215Ile
probably damaging
probably damaging
SNU182
TP53MutationMissenseENST00000269305.4
g.7578449C>T
g.7578449C>T
c.481G>A
c.481G>A
p.Ala161Thr
p.Ala161Thr
probably damaging
probably damaging
SNU449
TP53MutationMissenseENST00000269305.4
g.7577153C>T
g.7577153C>T
c.785G>A
c.785G>A
p.Gly262Asp (Splice)
p.Gly262Asp (Splice)
probably damaging
probably damaging
SNU475
TP53MutationMissenseENST00000269305.4
g.7577566T>C
g.7577566T>C
c.715A>G
c.715A>G
p.Asn239Asp
p.Asn239Asp
probably damaging
probably damaging
SNU475
TP53MutationMissenseENST00000269305.4
g.7578190T>C
g.7578190T>C
c.659A>G
c.659A>G
p.Tyr220Cys
p.Tyr220Cys
probably damaging
probably damaging
Huh7
TP53MutationMissenseENST00000269305.4
g.7577534C>A
g.7577534C>A
c.747G>T
c.747G>T
p.Arg249Ser
p.Arg249Ser
probably damaging
probably damaging
Mahlavu
TP53MutationMissenseENST00000269305.4
g.7577534C>A
g.7577534C>A
c.747G>T
c.747G>T
p.Arg249Ser
p.Arg249Ser
probably damaging
probably damaging
PLC.PRF5
TP53MutationMissenseENST00000269305.4
g.7577550C>G
g.7577550C>G
c.731G>C
c.731G>C
p.Gly244Ala
p.Gly244Ala
probably damaging
probably damaging
HLE
TP53MutationMissenseENST00000269305.4
g.7577550C>G
g.7577550C>G
c.731G>C
c.731G>C
p.Gly244Ala
p.Gly244Ala
probably damaging
probably damaging
HLF
TP53MutationMissenseENST00000455263.2
g.7576542A>G
g.7576542A>G
c.1036T>C
c.1036T>C
p.Ser346Pro
p.Ser346Pro
benign
benign
Li7
TP53MutationMissenseENST00000455263.2
g.7576572A>C
g.7576572A>C
c.1006T>G
c.1006T>G
p.Leu336Val
p.Leu336Val
damaging
damaging
Li7
TP53MutationMissenseENST00000269305.4
g.7579358C>A
g.7579358C>A
c.329G>T
c.329G>T
p.Arg110Leu
p.Arg110Leu
benign
benign
Huh1
TP53MutationMissenseENST00000269305.4
g.7577534C>A
g.7577534C>A
c.747G>T
c.747G>T
p.Arg249Ser
p.Arg249Ser
probably damaging
probably damaging
JHH4
TP53MutationMissenseENST00000269305.4
g.7577138C>G
g.7577138C>G
c.800G>C
c.800G>C
p.Arg267Pro
p.Arg267Pro
probably damaging
probably damaging
JHH7
TP53MutationMissenseENST00000269305.4
g.7579369G>C
g.7579369G>C
c.318C>G
c.318C>G
p.Ser106Arg
p.Ser106Arg
benign
benign
SNU368
TP53MutationMissenseENST00000269305.4
g.7578204A>C
g.7578204A>C
c.645T>G
c.645T>G
p.Ser215Arg
p.Ser215Arg
probably damaging
probably damaging
SNU739
TP53MutationMissenseENST00000269305.4
g.7577529A>T
g.7577529A>T
c.752T>A
c.752T>A
p.Ile251Asn
p.Ile251Asn
probably damaging
probably damaging
SNU878
TP53MutationTruncatingENST00000269305.4
g.7578475dup
g.7578475dup
c.455dup
c.455dup
p.Pro153AlafsX28
p.Pro153AlafsX28
damaging
damaging
HCC.3
TP53MutationTruncatingENST00000269305.4
g.7578177C>G
g.7578177C>G
c.672G>C
c.672G>C
p.Glu224Asp (Splice)
p.Glu224Asp (Splice)
damaging
damaging
HCC.1.1
TP53MutationTruncatingENST00000269305.4
g.7578440T>A
g.7578440T>A
c.490A>T
c.490A>T
p.Lys164X
p.Lys164X
damaging
damaging
SNU387
TP53MutationTruncatingENST00000269305.4
g.7578177C>T
g.7578177C>T
c.672G>A
c.672G>A
p.E224E (Splice)
p.E224E (Splice)
damaging
damaging
SNU398
TP53MutationTruncatingENST00000269305.4
g.7578556T>C
g.7578556T>C
c.376-2A>G
c.376-2A>G
p.Y126_splice
p.Y126_splice
damaging
damaging
SNU423
Codebase Soc. Coop.
info@codebase.it